Ⅰ 中美慢性肾脏病患病率对比 Ⅱ 出生体重对成年女性肾小球滤过率的作用Comparison of the prevalence of chronic kidney disease in China and the effect of birth weight on glomerular filtration rate in adult women 摘要:（摘要内容经过系统自动伪原创处理以避免复制，下载原文正常，内容请直接查看目录。） 对于慢性肾脏病种族差别的研究—中美慢性肾脏病得病率比较目标对2017年北京CKD风行病学筛查数据库与1999一2004年美国NHANES数据库停止比较剖析。商量中国与美国CKD得病率的种族差别。对对对对象象象象与与与方办法北京CKD筛查与美国NHANES研究都是多阶段分层整群抽样的人群普查，后者可从官方网站收费取得。从两个数据库分离选择年纪≥20岁者，消除个中预算肾小球滤过率（eGFR）》200 ml/min/1。73m2或《15 ml/min/1。73m2者，来自北京CKD数据库的13602名中国人及来自NHANES数据库的6755名白人，2467名黑人，西语论文范文，西语毕业论文，2988名西班牙裔人被归入研究。血肌酐丈量办法均矫准至美国克里夫兰临床试验室运用的办法，运用从新表达的简化MDRD公式和适于中国人的修改MDRD公式分离预算两国人的eGFR，《60 ml/min/1。73m2者界说为慢性肾功效不全（CRI）。卵白尿界说为尿白卵白肌酐比值（ACR）男性≥17mg/g，女性≥25mg/g。CRI和/或卵白尿阳性者诊断为CKD。结成果中国人卵白尿（9。25% v。s。12。01%， 15。70%， 13。49%）、CR（I1。37% v。s。9。35%， 5。24%， 3。40%。）、CKD（10。23% v。s。18。86%， 18。37%， 15。48%）得病率低于美国白人、黑人和西班牙裔人。中国人高血压、糖尿病、血脂异常、血汗管疾病、瘦削/超重的得病率低于美国人，但抽烟者的比例高于美国人，受教导水平低于白人但高于黑人和西班牙裔人。以上述风险身分校订后，中国人产生卵白尿、CRI、CKD的风险仍低于美国各类族。别的，除白人因超重/瘦削招致CKD的风险略低于中国人（OR0。972）和黑人因抽烟招致CKD的风险低于中国人（OR0。857）外，美国各类族因上述各类风险身分招致CKD产生的风险均高于中国人（OR 1。02至4。94）。本研究还发明，中国人的总CRI得病率固然低于美国人，但中国CRI患者处于某程度eGFR与其前一较高程度eGFR的人数的多风险身分校订后的比值与美国白人和西班牙裔人比拟逐步增高（与白人比拟，由eGFR 45一59ml/min/1。73m2的0。727增至eGFR 15一29ml/min/1。73m2的1。984；与西班牙裔人比拟，由eGFR 45一59ml/min/1。73m2的0。403增至eGFR 15一29ml/min/1。73m2的1。679），而上述各比值在中国人一直低于黑人（0。671至0。744），这提醒我们中国CRI患者停顿至更严重阶段的风险高于白人、西班牙裔人而低于黑人。结结论中国人CKD得病率低于美国各类族，部门与其CKD风险身分得病率较低有关，同时中国人对这些风险身分的易理性较低能够也是缘由之一。但中国的CRI患者的GFR降低至更低程度的风险高于白人、西班牙裔人而低于黑人。低出身体重对成年女性肾功效的作用目标研究低出身体重对成年女性肾小球滤过率的作用，并商量能够的缘由。办法查询拜访问卷搜集北京年夜学第一病院19一60岁女性职工的年纪、身高、体重、出身体重、高血压病史等材料，并检测空肚血糖、血脂、肌酐等目标。运用适于中国人的MDRD修改公式盘算eGFR。出身体重低于第一四分位数界说为LBW，第一四分位至第三四分位为正常出身体重（NBW）。eGFR跨越第95百分位数界说为肾小球高滤过，低于第5百分位数界说为肾功效降低。成果653名成年女性加入了本项研究。LBW者肾小球滤过率在30岁前与NBW者无差别（111。77ml/min/1。73m2 v。s。 111。74ml/min/1。73m2），30一39岁高于NBW者（107。70 ml/min/1。73m2 v。s。 103。44ml/min/1。73m2），重要与超重的作用有关，40岁后低于NBW者（91。29ml/min/1。73m2 v。s。 98。12ml/min/1。73m2），与超重、高脂血症和空肚血糖增高的作用有关。LBW是19一29岁（OR 2。88，95%CI 1。02一8。15））和30一39岁（OR 5。84，95%CI 1。1一31。01）产生肾小球高滤过和40一60岁产生肾功效降低（OR 6。5，95%CI 1。25一33。7）的自力风险身分。结论在代谢性身分的感化下，LBW成年女性在青年早期绝关于NBW者表示为肾脏高滤过，而在中年后表示为肾功效降低。 Abstract: The study of racial differences in chronic kidney disease - the comparison of chronic kidney disease incidence rate between China and the United States in 2017 Beijing CKD epidemiology screening database and 1999 a 2004 U.S. NHANES database to compare the analysis. To discuss the racial differences in the incidence of CKD in China and the United states. On the object of the elephant and the method of Beijing and the United States CKD screening and the United States NHANES research are multi-stage stratified cluster sampling of the population census, the latter can be obtained from the official website. Select the age of more than 20 years' separation from the two database, the budget to eliminate the glomerular filtration rate (eGFR) "200 ml/min/1. 73m2 or "15 ml/min/1". 73m2, from the Beijing CKD database of 13602 Chinese and 6755 white, 2467 black, 2988 Hispanic people from the NHANES database were included in the study. Serum creatinine measurement methods were straightening quasi to the Cleveland Clinic lab application way, application from new expression of simplified MDRD formula and suitable for Chinese modified MDRD formula separation EGFR budget the peoples of our two countries, "60 ml/min/1. 73m2 is defined as chronic renal insufficiency (CRI). Proteinuria is defined as urinary protein creatinine ratio (ACR) = 17mg/g 25mg/g = male, female. CRI and / or proteinuria were diagnosed as CKD. Node results Chinese proteinuria (9. 25% v. S. 12. 01%, 15. 13, 70%. (49%), CR (I1). 37% v. S. 9. 5, 35%. 3, 24%. 40%. CKD (10. 23% v. S. 18. 18, 86%. 15, 37%. 48%) the incidence of disease is lower than that of white, black and Hispanic Americans. Chinese hypertension, diabetes, dyslipidemia, cardiovascular disease, obesity / overweight sick rate than Americans, but the proportion of smokers higher than that of Americans, the education level below whites but higher than blacks and Hispanics. In the book, risk, risk Chinese have proteinuria, CRI, CKD is still lower than that of various kinds of American family. In addition to the other, because of the risk of overweight / obese white lead CKD is slightly lower than Chinese (OR0. 972) and the risk of CKD caused by smoking is lower than that of the Chinese people (OR0). 857) outside, all kinds of family of the United States because of all kinds of risk factor to incur the risk of CKD is higher than the Chinese people (OR 1). 02 to 4. 94). The study also found, Chinese general CRI sicken rate although less than Americans, but Chinese patients with CRI in order number of a certain degree of EGFR and a higher degree of EGFR multi risk body, the ratio and American whites and Hispanics compared gradually increased (compared with whites. By EGFR 45 59ml/min/1. 73m2 0. 727 to eGFR 15 a 29ml/min/1. 73m2 1. 984; compared with Hispanic people, by eGFR 45 a 59ml/min/1. 73m2 0. 403 to eGFR 15 a 29ml/min/1. 73m2 1. 679), and these ratios in the Chinese people have been lower than the black (0). 671 to 0. 744), it reminds us that the risk of CRI patients in China to a more serious stage is higher than that of whites, Hispanics and blacks. Conclusion Chinese CKD disease rate is lower than the United States all kinds of family, the Department of risk factor and CKD disease rate is relatively low, while the Chinese people on these risk factors of the reason is low can also be one of the reasons. But the risk of GFR in Chinese patients with CRI was lower than that of whites, Hispanics, and lower than blacks. Low body weight on the effect of kidney function of adult women's goal to study the effect of low body weight on the glomerular filtration rate of adult women, and to discuss the reasons for the. Way to query visit questionnaire to gather in Beijing University First Hospital 19 A 60 year old female workers age, height, weight, birth weight, hypertension and other materials and detection of an empty stomach blood sugar, blood lipid, creatinine. Application of MDRD modified formula for the Chinese people to calculate eGFR. Birth weight is lower than the first four quantile is defined as LBW, the first four points to three or four points for normal birth weight (NBW). EGFR across the ninety-fifth percentile is defined as glomerular hyperfiltration, below the fifth percentile of reduced renal function. Results 653 adult women joined the research. LBW glomerular filtration rate had no difference at the age of 30 and NBW (111. 77ml/min/1. V 73m2. S. 111. 74ml/min/1. 73m2), 39 A 30 year old is higher than NBW (107). 70 ml/min/1. V 73m2. S. 103. 44ml/min/1. 73m2), an important influence on the impact of overweight, after 40 years of age less than NBW (91). 29ml/min/1. V 73m2. S. 98. 12ml/min/1. 73m2), and the effects of overweight, hyperlipidemia and empty stomach blood glucose. LBW is 19 A 29 year old (OR 2. 88, 95%CI 1. 02 a 8. (15) and 39 A 30 year old (OR 5). 84, 95%CI 1. 1 a 31. 01) produce high glomerular filtration and 60 of a 40 year old to produce a reduction in renal function (OR 6). 5, 95%CI 1. 25 a 33. Independent risk factor of 7). Conclusions in the metabolic status of the probation, LBW adult women in the early age of NBW is absolute in the kidney of high filtration, and in the middle of the lower. 目录: |
